| Name | Edition | Colour | Type | Cost | Power | Rarity | $ |
|---|---|---|---|---|---|---|---|
| Sima Yi, Wei Field Marshal | P3K | Black | Summon Creature - Legend | 5B | */4 | Rare | 9.07 |
| Simian Brawler | CS | Green | Creature - Ape Warrior | 3G | 3/3 | Common | 3.55 |
| Simian Grunts | UL | Green | Summon Apes | 2G | 3/4 | Common | 2.61 |
| Simian Spirit Guide | PC | Red | Creature - Ape Spirit | 2R | 2/2 | Common | 0.28 |
| Simic Basilisk | DI | Green | Creature - Basilisk Mutant | 4GG | 0/0 | Uncommon | 3.51 |
| Simic Growth Chamber | DI | Land | Land | Common | 3.30 | ||
| Simic Guildmage | DI | Multi | Creature - Elf Wizard | (U/G)(U/G) | 2/2 | Uncommon | 3.52 |
| Simic Initiate | DI | Green | Creature - Human Mutant | G | 0/0 | Common | 3.33 |
| Simic Ragworm | DI | Green | Creature - Worm | 3G | 3/3 | Common | 3.33 |
| Simic Signet | DI | Artifact | Artifact | 2 | Common | 3.36 | |
| Simic Sky Swallower | DI | Multi | Creature - Leviathan | 6/6 | Rare | 5.66 | |
| Simoon | VI | Unknown | Instant | RG | Uncommon | 2.48 | |
| Simoon | IN | Multi | Instant | RG | Uncommon | 2.63 | |
| Simplify | OD | Green | Sorcery | G | Common | 0.12 | |
| Simulacrum | UN | Black | Instant | 1B | Uncommon | 3.10 | |
| Simulacrum | RV | Black | Instant | 1B | Uncommon | 2.42 | |
| Simulacrum | B | Black | Instant | 1B | Uncommon | 4.92 | |
| Simulacrum | A | Black | Instant | 1B | Uncommon | 5.87 | |
| Simulacrum | 4E | Black | Instant | 1B | Uncommon | 2.96 | |
| Simulacrum | CE | Black | Instant | 1B | Uncommon | 14.41 |